A Comparative Study of the effect of aqueous extract of Vitex agnus-castus plant on male and female’s liver’s enzymes of mice exposed to oxidative stress

This study was conducted to determine the Protective effect of aqueous extracts Vitex agnus castus plant both doses, Normal active does(50mg/kg) and double (100mg/kg) in liver enzymes comported deferent it between male female’s Mice, that exposed oxidative stress induced by hydrogen peroxide (0.5%) with drinking water for (30) days, there were distributed into 10 groups which are (control group, H2O2 dose + H2O2, vitamin E, Vitex+ Vitex, Vitex+H2O2, Vitex+H2O2+vitamin E .
 The results showed led a significant increase (p≤0.01) ALT, AST ALP levels, compared control no female’s, treating (50 &100 mg/kg) decrease levels compare infected group , treatment Vitamin It concluded from current study, important role as an antioxidant through its curbing harmful effects certain types free radicals within body thus repair damage done changes mices enzyme over exposure (H2O2. (